David Sinclair’s book: Lifespan

I rarely read fiction books. When I read, I almost always read non-fiction books, in hopes of learning something new. I love to learn, so reading non-fiction is a labor of love. But, labor is labor, right?

My wife reads mostly fiction books. Every so often, she finds a book and she cannot put it down until she finishes it. I can probably count the times one one hand that that has happened to me. But it happened this weekend.

Dr David Sinclair is a Director at the Paul F. Glenn Laboratories for the Biological Mechanisms of Aging at Harvard. He’s a biologist and is one of the world’s leading researchers in the field of aging (or anti-aging).

He released a book this month called “Lifespan: Why We Age — And Why We Don’t Have To”. I devoured it this weekend. I could not put it down. In fact, it’s probably one I’ll want to re-read some day.

I’ve been following Dr Sinclair for some time now, but he absolutely blew my mind with what he sees coming down the pike in the realm of anti-aging. I mean, I knew he was working on some interesting stuff in a quest to prolong a healthy life, but then he surfaced some next-level research that takes us into the world of Benjamin Button!

He makes a bold claim that Aging is a disease. And current science is — I hate to say wasting — but it is not optimizing resources by studying individual diseases. It’s like playing whack-a-mole. Dr Sinclair contends that many of these diseases that occur in “old age” are merely symptoms of aging. And there is a “cure” for aging.

I don’t want to ruin it for you, but holy crap, this possibility (imminent certainty?) really makes you think about the implications to society, to our planet, to humanity and Dr Sinclair touches on all of this.

It was awesome. I highly recommend!


If you don’t know who Dr David Sinclair is, here are resources to learn about him:

[Sept 13, 2018] Crazy/Genius podcast: Can Can We Extend Human Lifespans to 150 https://www.theatlantic.com/ideas/archive/2018/09/can-science-cure-aging/570121/

[Nov 5, 2018] Peter Attia podcast: https://peterattiamd.com/davidsinclair/

[Jan 29, 2019] Joe Rogan podcast: https://youtu.be/HOTS0HS7aq4

[Apr 22, 2019] Modern Wisdom podcast: https://youtu.be/J736mfy7KEg

Lifespan (https://lifespanbook.com) book launched Sept 10, 2019:

[Sept 1, 2019] Dr Mercola podcast: http://podcast.mercola.com/dr-mercola-interviews-dr-david-sinclair-on-extending-your-lifespan

[Sept 9, 2019] Peter Attia podcast: https://peterattiamd.com/davidsinclair2/

[Sept 10, 2019] Joe Rogan podcast: https://youtu.be/ZGLL77wYxe8

[Sept 11, 2019] Dr Mark Hyman podcast: https://youtu.be/CVUhI7mUWkU

[Sept 12, 2019] Bulletproof radio podcast: https://youtu.be/PTQZjuGlj_0 or https://blog.daveasprey.com/david-sinclair-626/

[Sept 18, 2019] Finding Mastery podcast: https://findingmastery.net/david-sinclair/

[Sept 19, 2019] Armchair Nutritionist: https://soundcloud.com/user-872173606/an21-david-sinclair

[Sept 19, 2019] Impact Theory podcast: https://youtu.be/IEz1P4i1P7s

[Sept 20, 2019] Peerspectrum podcast: https://peerspectrum.com/2019/09/20/crossing-medicines-last-perimeter-aging-and-longevity-with-harvard-geneticist-david-sinclair-phd/

[Sept 23, 2019] Freedom Pact podcast: https://soundcloud.com/freedompactpodcast/58-professor-david-sinclair-why-we-age-and-why-we-dont-have-to

How Much Time do you REALLY Have?

Would you change anything if you, literally, knew when your time is up? Seems we each have an explicit biological clock embedded in our DNA.

This article talks about how researchers found that your Epigenetic clock can calculate biological age and predict your lifespan.

“Some individuals who fill their lives with fitness and healthy habits die younger than peers who live a much less healthy life. New research into the epigenetics of aging sheds some fresh light on the perplexing phenomenon of premature aging.”

It’s based on this research paper.

I thought this was super interesting.

Loads of implications:

  • Would you retire earlier or later based on your biological age?
  • Surely, this is going to have a tremendous effect on the Insurance industry.
    • I wonder how long until the industry adopts this as common practice to set your premiums.
  • Now that we know the marker (or measure), can we work to improve or manipulate it. (this is all over my head, I don’t even know if that’s a valid question)